Episode 217 - Building Trust in the Next Generation of Healthcare AI

In this episode, Dr. Haider Warraich, Program Manager, Scalable Solutions at Advanced Research Projects Agency for Health (ARPA-H), explains why building trust, not just advancing technology, is key to unlocking the next generation of healthcare AI. Leading ARPA-H’s ADVOCATE program, he shares how the agency is accelerating the development of patient-facing, agentic AI designed to improve outcomes for people living with heart failure, while simultaneously building the regulatory and evaluation infrastructure needed to safely bring these innovations into clinical practice.

Dr. Warraich argues that healthcare must innovate and evaluate AI in parallel. As AI development accelerates, lasting trust will depend on rigorous clinical evidence, familiar regulatory pathways, and real-time post-market monitoring. He also encourages innovators to think boldly, noting that breakthrough ideas often seem unrealistic before they become reality.

Dr. Warraich sees AI alignment, patient-centered technologies for high-need populations, and high-fidelity healthcare simulations as the next frontiers of innovation. He envisions that the future of healthcare AI will be shaped by bold ideas grounded in scientific rigor, transparent evaluation, and close collaboration between innovators, regulators, and health systems. That’s how the industry will build the trust needed to scale AI and improve patient care. Take a listen.

This guest appearance was facilitated through conversations initiated at HIMSS.